America's most beloved depressed cartoonist is off the couch and back to making us laugh at his misery! This long-awaited full-color oversized comic brings you right into the action! This time around Brunetti taps into his academic side with biographies of Piet Mondrian, Soren Kierkegaard, Erik Satie, James Thurber, Francoise Hardy, Louise Brooks, and J.K. Huysmans. And if that weren't enough, there are tributes to Charles Schulz and the Marx Brothers; a step-by-step guide on how to draw cartoons; and strips on misogyny, 9/11, suicidal ideation, and abortive crushes on waitresses PLUS so much more.

Winner, Outstanding Comic, 2006 Ignatz Awards

2007 Eisner Award nominee: Best Humor Publication, Best Writer/Artist — Humor, Best Lettering

2007 Harvey Award nominee: Best Single Issue or Story

"Schizo excels not only because of the material within, but also because of the picture it paints of its own creator, beseiged by loathing and doubt." – Christopher Butcher

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